Cargando…

Dynamic Cross Talk Model of the Epithelial Innate Immune Response to Double-Stranded RNA Stimulation: Coordinated Dynamics Emerging from Cell-Level Noise

We present an integrated dynamical cross-talk model of the epithelial innate immune reponse (IIR) incorporating RIG-I and TLR3 as the two major pattern recognition receptors (PRR) converging on the RelA and IRF3 transcriptional effectors. bioPN simulations reproduce biologically relevant gene-and pr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bertolusso, Roberto, Tian, Bing, Zhao, Yingxin, Vergara, Leoncio, Sabree, Aqeeb, Iwanaszko, Marta, Lipniacki, Tomasz, Brasier, Allan R., Kimmel, Marek
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977818/ https://www.ncbi.nlm.nih.gov/pubmed/24710104 http://dx.doi.org/10.1371/journal.pone.0093396

Ejemplares similares

The dependence of expression of NF-κB-dependent genes: statistics and evolutionary conservation of control sequences in the promoter and in the 3′ UTR
por: Iwanaszko, Marta, et al.
Publicado: (2012)

Correction: Dynamic Cross Talk Model of the Epithelial Innate Immune Response to Double-Stranded RNA Stimulation: Coordinated Dynamics Emerging from Cell-Level Noise
Publicado: (2014)

Single TNFα trimers mediating NF-κB activation: stochastic robustness of NF-κB signaling
por: Lipniacki, Tomasz, et al.
Publicado: (2007)

Mutation, drift and selection in single-driver hematologic malignancy: Example of secondary myelodysplastic syndrome following treatment of inherited neutropenia
por: Wojdyla, Tomasz, et al.
Publicado: (2019)

Cell fate in antiviral response arises in the crosstalk of IRF, NF-κB and JAK/STAT pathways
por: Czerkies, Maciej, et al.
Publicado: (2018)

The Hexosamine Biosynthetic Pathway Links Innate Inflammation With Epithelial-Mesenchymal Plasticity in Airway Remodeling
por: Brasier, Allan R., et al.
Publicado: (2021)

NF-κB and IRF pathways: cross-regulation on target genes promoter level
por: Iwanaszko, Marta, et al.
Publicado: (2015)

Mathematical modelling reveals unexpected inheritance and variability patterns of cell cycle parameters in mammalian cells
por: Mura, Marzena, et al.
Publicado: (2019)

Antagonism between viral infection and innate immunity at the single-cell level
por: Grabowski, Frederic, et al.
Publicado: (2023)

Microarray experiments and factors which affect their reliability
por: Jaksik, Roman, et al.
Publicado: (2015)

RELA∙8-Oxoguanine DNA Glycosylase1 Is an Epigenetic Regulatory Complex Coordinating the Hexosamine Biosynthetic Pathway in RSV Infection
por: Xu, Xiaofang, et al.
Publicado: (2022)

Clustering reveals limits of parameter identifiability in multi-parameter models of biochemical dynamics
por: Nienałtowski, Karol, et al.
Publicado: (2015)

Slow nucleosome dynamics set the transcriptional speed limit and induce RNA polymerase II traffic jams and bursts
por: Mines, Robert C., et al.
Publicado: (2022)

Mitofusin 2, a key coordinator between mitochondrial dynamics and innate immunity
por: Kim, In Soo, et al.
Publicado: (2021)

RSV Reprograms the CDK9•BRD4 Chromatin Remodeling Complex to Couple Innate Inflammation to Airway Remodeling
por: Brasier, Allan R.
Publicado: (2020)

Mother–Fetus Immune Cross-Talk Coordinates “Extrinsic”/“Intrinsic” Embryo Gene Expression Noise and Growth Stability
por: Babochkina, Tatyana Ivanovna, et al.
Publicado: (2022)

Pareto-based evaluation of national responses to COVID-19 pandemic shows that saving lives and protecting economy are non-trade-off objectives
por: Kochańczyk, Marek, et al.
Publicado: (2021)

Multiparticle Dynamics 1998: Summary talk
por: Dremin, I M
Publicado: (2000)

Cheap talk communication with dynamic information searching
por: Zhang, Yongjie, et al.
Publicado: (2016)

Noise in nonlinear dynamical systems
por: McClintock, P V E, et al.
Publicado: (1989)

Noise in nonlinear dynamical systems
por: McClintock, P V E, et al.
Publicado: (1989)

Noise in nonlinear dynamical systems
por: McClintock, P V E, et al.
Publicado: (1989)

Transverse Beam Dynamics with Noise
por: Ellison, J A, et al.
Publicado: (1996)

Super-spreading events initiated the exponential growth phase of COVID-19 with ℛ(0) higher than initially estimated
por: Kochańczyk, Marek, et al.
Publicado: (2020)

The Spread of SARS-CoV-2 Variant Omicron with a Doubling Time of 2.0–3.3 Days Can Be Explained by Immune Evasion
por: Grabowski, Frederic, et al.
Publicado: (2022)

Alternative mRNA Processing of Innate Response Pathways in Respiratory Syncytial Virus (RSV) Infection
por: Xu, Xiaofang, et al.
Publicado: (2021)

Coordinate activities of BRD4 and CDK9 in the transcriptional elongation complex are required for TGFβ-induced Nox4 expression and myofibroblast transdifferentiation
por: Ijaz, Talha, et al.
Publicado: (2017)

Innate Immunity Interactome Dynamics
por: Elzawahry, Asmaa, et al.
Publicado: (2014)

The IRE1α–XBP1s Arm of the Unfolded Protein Response Activates N-Glycosylation to Remodel the Subepithelial Basement Membrane in Paramyxovirus Infection
por: Zhao, Yingxin, et al.
Publicado: (2022)

TLR Cross-talk Confers Specificity to Innate Immunity
por: Tan, Rebecca S. T., et al.
Publicado: (2014)

Stochastic Hypothesis of Transition from Inborn Neutropenia to AML: Interactions of Cell Population Dynamics and Population Genetics
por: Kimmel, Marek, et al.
Publicado: (2013)

Identification of dynamical systems with small noise
por: Kutoyants, Yu
Publicado: (1994)

Dynamically weighted clustering with noise set
por: Shen, Yijing, et al.
Publicado: (2010)

Longitudinal beam dynamics with RF noise
por: Shih, H J, et al.
Publicado: (1994)

Longitudinal beam dynamics with RF noise
por: Shih, H J, et al.
Publicado: (1992)

Noise representations of open system dynamics
por: Szańkowski, Piotr, et al.
Publicado: (2020)

Dynamics of double strand breaks and chromosomal translocations
por: Iarovaia, Olga V, et al.
Publicado: (2014)

Coordination dynamics issues and trends
por: Jirsa, Viktor, et al.
Publicado: (2004)

The coordination dynamics of social neuromarkers
por: Tognoli, Emmanuelle, et al.
Publicado: (2015)

Coordination Dynamics in Cognitive Neuroscience
por: Bressler, Steven L., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_sk9ci2vtah2l8i270voprq055k