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Prepuberal Stimulation of 5-HT7-R by LP-211 in a Rat Model of Hyper-Activity and Attention-Deficit: Permanent Effects on Attention, Brain Amino Acids and Synaptic Markers in the Fronto-Striatal Interface

The cross-talk at the prefronto-striatal interface involves excitatory amino acids, different receptors, transducers and modulators. We investigated long-term effects of a prepuberal, subchronic 5-HT7-R agonist (LP-211) on adult behaviour, amino acids and synaptic markers in a model for Attention-De...

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Detalles Bibliográficos
Autores principales: Ruocco, Lucia A., Treno, Concetta, Gironi Carnevale, Ugo A., Arra, Claudio, Boatto, Gianpiero, Nieddu, Maria, Pagano, Cristina, Illiano, Placido, Barbato, Fabiana, Tino, Angela, Carboni, Ezio, Laviola, Giovanni, Lacivita, Enza, Leopoldo, Marcello, Adriani, Walter, Sadile, Adolfo G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977819/
https://www.ncbi.nlm.nih.gov/pubmed/24709857
http://dx.doi.org/10.1371/journal.pone.0083003