Measuring Turnover of SIV DNA in Resting CD4+ T Cells Using Pyrosequencing: Implications for the Timing of HIV Eradication Therapies

Resting CD4+ T cells are a reservoir of latent HIV-1. Understanding the turnover of HIV DNA in these cells has implications for the development of eradication strategies. Most studies of viral latency focus on viral persistence under antiretroviral therapy (ART). We studied the turnover of SIV DNA r...

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Detalles Bibliográficos
Autores principales: Reece, Jeanette C., Martyushev, Alexey, Petravic, Janka, Grimm, Andrew, Gooneratne, Shayarana, Amaresena, Thakshila, De Rose, Robert, Loh, Liyen, Davenport, Miles P., Kent, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977820/
https://www.ncbi.nlm.nih.gov/pubmed/24710023
http://dx.doi.org/10.1371/journal.pone.0093330

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