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LRIG1 as a Potential Novel Marker for Neoplastic Transformation in Ocular Surface Squamous Neoplasia
The leucine rich repeats and immunoglobulin-like protein 1 (LRIG1) is a newly discovered negative regulator of epidermal growth factor receptor (EGFR) and a proposed tumor suppressor. It is not universally downregulated in human cancers, and its role in neoplastic transformation and tumorigenesis is...
Autores principales: | Nagata, Maho, Nakamura, Takahiro, Sotozono, Chie, Inatomi, Tsutomu, Yokoi, Norihiko, Kinoshita, Shigeru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977825/ https://www.ncbi.nlm.nih.gov/pubmed/24709893 http://dx.doi.org/10.1371/journal.pone.0093164 |
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