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Oncostatin M Mediates STAT3-Dependent Intestinal Epithelial Restitution via Increased Cell Proliferation, Decreased Apoptosis and Upregulation of SERPIN Family Members
OBJECTIVE: Oncostatin M (OSM) is produced by activated T cells, monocytes, and dendritic cells and signals through two distinct receptor complexes consisting of gp130 and LIFR (I) or OSMR-β and gp130 (II), respectively. Aim of this study was to analyze the role of OSM in intestinal epithelial cells...
Autores principales: | Beigel, Florian, Friedrich, Matthias, Probst, Corina, Sotlar, Karl, Göke, Burkhard, Diegelmann, Julia, Brand, Stephan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977870/ https://www.ncbi.nlm.nih.gov/pubmed/24710357 http://dx.doi.org/10.1371/journal.pone.0093498 |
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