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Mitochondria directly donate their membrane to form autophagosomes during a novel mechanism of parkin-associated mitophagy
BACKGROUND: Autophagy (macroautophagy), a cellular process of “self-eating”, segregates damaged/aged organelles into vesicles, fuses with lysosomes, and enables recycling of the digested materials. The precise origin(s) of the autophagosome membrane is unclear and remains a critical but unanswered q...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977894/ https://www.ncbi.nlm.nih.gov/pubmed/24669863 http://dx.doi.org/10.1186/2045-3701-4-16 |