Arsenic trioxide inhibits Hedgehog, Notch and stem cell properties in glioblastoma neurospheres

BACKGROUND: Notch and Hedgehog signaling have been implicated in the pathogenesis and stem-like characteristics of glioblastomas, and inhibitors of the pathways have been suggested as new therapies for these aggressive tumors. It has also been reported that targeting both pathways simultaneously can...

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Detalles Bibliográficos
Autores principales: Ding, Dacheng, Lim, Kah Suan, Eberhart, Charles G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977902/
https://www.ncbi.nlm.nih.gov/pubmed/24685274
http://dx.doi.org/10.1186/2051-5960-2-31

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977902/
https://www.ncbi.nlm.nih.gov/pubmed/24685274
http://dx.doi.org/10.1186/2051-5960-2-31

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