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Arsenic trioxide inhibits Hedgehog, Notch and stem cell properties in glioblastoma neurospheres
BACKGROUND: Notch and Hedgehog signaling have been implicated in the pathogenesis and stem-like characteristics of glioblastomas, and inhibitors of the pathways have been suggested as new therapies for these aggressive tumors. It has also been reported that targeting both pathways simultaneously can...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977902/ https://www.ncbi.nlm.nih.gov/pubmed/24685274 http://dx.doi.org/10.1186/2051-5960-2-31 |