R-loops in bacterial transcription: Their causes and consequences

Nascent untranslated transcripts in bacteria are prone to generating RNA-DNA hybrids (R-loops); Rho-dependent transcription termination acts to reduce their prevalence. Here we discuss the mechanisms of R-loop formation and growth inhibition in bacteria.

Detalles Bibliográficos
Autores principales: Gowrishankar, J, Leela, J Krishna, Anupama, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Point of View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977913/
https://www.ncbi.nlm.nih.gov/pubmed/23756343
http://dx.doi.org/10.4161/trns.25101
_version_ 1782310477229981696
author Gowrishankar, J
Leela, J Krishna
Anupama, K
author_facet Gowrishankar, J
Leela, J Krishna
Anupama, K
author_sort Gowrishankar, J
collection PubMed
description Nascent untranslated transcripts in bacteria are prone to generating RNA-DNA hybrids (R-loops); Rho-dependent transcription termination acts to reduce their prevalence. Here we discuss the mechanisms of R-loop formation and growth inhibition in bacteria.
format Online
Article
Text
id pubmed-3977913
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher Landes Bioscience
record_format MEDLINE/PubMed
spelling pubmed-39779132014-04-14 R-loops in bacterial transcription: Their causes and consequences Gowrishankar, J Leela, J Krishna Anupama, K Transcription Point of View Nascent untranslated transcripts in bacteria are prone to generating RNA-DNA hybrids (R-loops); Rho-dependent transcription termination acts to reduce their prevalence. Here we discuss the mechanisms of R-loop formation and growth inhibition in bacteria. Landes Bioscience 2013-07-01 2013-06-11 /pmc/articles/PMC3977913/ /pubmed/23756343 http://dx.doi.org/10.4161/trns.25101 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Point of View
Gowrishankar, J
Leela, J Krishna
Anupama, K
R-loops in bacterial transcription: Their causes and consequences
title R-loops in bacterial transcription: Their causes and consequences
title_full R-loops in bacterial transcription: Their causes and consequences
title_fullStr R-loops in bacterial transcription: Their causes and consequences
title_full_unstemmed R-loops in bacterial transcription: Their causes and consequences
title_short R-loops in bacterial transcription: Their causes and consequences
title_sort r-loops in bacterial transcription: their causes and consequences
topic Point of View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977913/
https://www.ncbi.nlm.nih.gov/pubmed/23756343
http://dx.doi.org/10.4161/trns.25101
work_keys_str_mv AT gowrishankarj rloopsinbacterialtranscriptiontheircausesandconsequences
AT leelajkrishna rloopsinbacterialtranscriptiontheircausesandconsequences
AT anupamak rloopsinbacterialtranscriptiontheircausesandconsequences

Ejemplares similares