Cargando…

The N-Terminal Cleavage of Chondromodulin-I in Growth-Plate Cartilage at the Hypertrophic and Calcified Zones during Bone Development

Chondromodulin-I (ChM-I) is a 20–25 kDa anti-angiogenic glycoprotein in cartilage matrix. In the present study, we identified a novel 14-kDa species of ChM-I by immunoblotting, and purified it by immunoprecipitation with a newly raised monoclonal antibody against ChM-I. The N-terminal amino acid seq...

Descripción completa

Detalles Bibliográficos
Autores principales: Miura, Shigenori, Kondo, Jun, Takimoto, Aki, Sano-Takai, Hiroko, Guo, Long, Shukunami, Chisa, Tanaka, Hideyuki, Hiraki, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977995/
https://www.ncbi.nlm.nih.gov/pubmed/24710035
http://dx.doi.org/10.1371/journal.pone.0094239