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Endotoxin Induces Fibrosis in Vascular Endothelial Cells through a Mechanism Dependent on Transient Receptor Protein Melastatin 7 Activity
The pathogenesis of systemic inflammatory diseases, including endotoxemia-derived sepsis syndrome, is characterized by endothelial dysfunction. It has been demonstrated that the endotoxin lipopolysaccharide (LPS) induces the conversion of endothelial cells (ECs) into activated fibroblasts through en...
Autores principales: | Echeverría, Cesar, Montorfano, Ignacio, Hermosilla, Tamara, Armisén, Ricardo, Velásquez, Luis A., Cabello-Verrugio, Claudio, Varela, Diego, Simon, Felipe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978016/ https://www.ncbi.nlm.nih.gov/pubmed/24710004 http://dx.doi.org/10.1371/journal.pone.0094146 |
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