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Sarm1 deficiency impairs synaptic function and leads to behavioral deficits, which can be ameliorated by an mGluR allosteric modulator

Innate immune responses have been shown to influence brain development and function. Dysregulation of innate immunity is significantly associated with psychiatric disorders such as autism spectrum disorders and schizophrenia, which are well-known neurodevelopmental disorders. Recent studies have rev...

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Detalles Bibliográficos
Autores principales: Lin, Chia-Wen, Chen, Chiung-Ya, Cheng, Sin-Jhong, Hu, Hsiao-Tang, Hsueh, Yi-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978259/
https://www.ncbi.nlm.nih.gov/pubmed/24744698
http://dx.doi.org/10.3389/fncel.2014.00087