RNA editing in RHOQ promotes invasion potential in colorectal cancer

RNA editing can increase RNA sequence variation without altering the DNA sequence. By comparing whole-genome and transcriptome sequence data of a rectal cancer, we found novel tumor-associated increase of RNA editing in ras homologue family member Q (RHOQ) transcripts. The adenosine-to-inosine (A-to...

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Detalles Bibliográficos
Autores principales: Han, Sae-Won, Kim, Hwang-Phill, Shin, Jong-Yeon, Jeong, Eun-Goo, Lee, Won-Chul, Kim, Keon Young, Park, Sang Youn, Lee, Dae-Won, Won, Jae-Kyung, Jeong, Seung-Yong, Park, Kyu Joo, Park, Jae-Gahb, Kang, Gyeong Hoon, Seo, Jeong-Sun, Kim, Jong-Il, Kim, Tae-You
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978269/
https://www.ncbi.nlm.nih.gov/pubmed/24663214
http://dx.doi.org/10.1084/jem.20132209

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