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Oxidative metabolism enables Salmonella evasion of the NLRP3 inflammasome
Microbial infection triggers assembly of inflammasome complexes that promote caspase-1–dependent antimicrobial responses. Inflammasome assembly is mediated by members of the nucleotide binding domain leucine-rich repeat (NLR) protein family that respond to cytosolic bacterial products or disruption...
Autores principales: | Wynosky-Dolfi, Meghan A., Snyder, Annelise G., Philip, Naomi H., Doonan, Patrick J., Poffenberger, Maya C., Avizonis, Daina, Zwack, Erin E., Riblett, Amber M., Hu, Baofeng, Strowig, Till, Flavell, Richard A., Jones, Russell G., Freedman, Bruce D., Brodsky, Igor E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978275/ https://www.ncbi.nlm.nih.gov/pubmed/24638169 http://dx.doi.org/10.1084/jem.20130627 |
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