Evaluating the impact of genotype errors on rare variant tests of association

The new class of rare variant tests has usually been evaluated assuming perfect genotype information. In reality, rare variant genotypes may be incorrect, and so rare variant tests should be robust to imperfect data. Errors and uncertainty in SNP genotyping are already known to dramatically impact s...

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Detalles Bibliográficos
Autores principales: Cook, Kaitlyn, Benitez, Alejandra, Fu, Casey, Tintle, Nathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978329/
https://www.ncbi.nlm.nih.gov/pubmed/24744770
http://dx.doi.org/10.3389/fgene.2014.00062

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