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Mixed Fungal Infection (Aspergillus, Mucor, and Candida) of Severe Hand Injury

Severe hand injuries are almost always heavily contaminated and hence wound infections in those patients are frequent. Fungal wound infections are rare in immunocompetent patients. A case of mixed fungal infection (Aspergillus, Mucor, and Candida) was documented in a young male patient, with a sever...

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Autores principales: Obradovic-Tomasev, Milana, Popovic, Aleksandra, Vuckovic, Nada, Jovanovic, Mladen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978409/
https://www.ncbi.nlm.nih.gov/pubmed/24782933
http://dx.doi.org/10.1155/2014/954186
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author Obradovic-Tomasev, Milana
Popovic, Aleksandra
Vuckovic, Nada
Jovanovic, Mladen
author_facet Obradovic-Tomasev, Milana
Popovic, Aleksandra
Vuckovic, Nada
Jovanovic, Mladen
author_sort Obradovic-Tomasev, Milana
collection PubMed
description Severe hand injuries are almost always heavily contaminated and hence wound infections in those patients are frequent. Fungal wound infections are rare in immunocompetent patients. A case of mixed fungal infection (Aspergillus, Mucor, and Candida) was documented in a young male patient, with a severe hand injury caused by a corn picker. The diagnosis of fungal infection was confirmed microbiologically and histopathologically. The treatment was conducted with repeated surgical necrectomy and administration of antifungal drugs according to the antimycogram. After ten weeks the patient was successfully cured. The aggressive nature of Mucor and Aspergillus skin infection was described. A high degree of suspicion and a multidisciplinary approach are necessary for an early diagnosis and the initiation of the adequate treatment. Early detection, surgical intervention, and appropriate antifungal therapy are essential in the treatment of this rare infection that could potentially lead to loss of limbs or even death.
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spelling pubmed-39784092014-04-29 Mixed Fungal Infection (Aspergillus, Mucor, and Candida) of Severe Hand Injury Obradovic-Tomasev, Milana Popovic, Aleksandra Vuckovic, Nada Jovanovic, Mladen Case Rep Infect Dis Case Report Severe hand injuries are almost always heavily contaminated and hence wound infections in those patients are frequent. Fungal wound infections are rare in immunocompetent patients. A case of mixed fungal infection (Aspergillus, Mucor, and Candida) was documented in a young male patient, with a severe hand injury caused by a corn picker. The diagnosis of fungal infection was confirmed microbiologically and histopathologically. The treatment was conducted with repeated surgical necrectomy and administration of antifungal drugs according to the antimycogram. After ten weeks the patient was successfully cured. The aggressive nature of Mucor and Aspergillus skin infection was described. A high degree of suspicion and a multidisciplinary approach are necessary for an early diagnosis and the initiation of the adequate treatment. Early detection, surgical intervention, and appropriate antifungal therapy are essential in the treatment of this rare infection that could potentially lead to loss of limbs or even death. Hindawi Publishing Corporation 2014 2014-03-13 /pmc/articles/PMC3978409/ /pubmed/24782933 http://dx.doi.org/10.1155/2014/954186 Text en Copyright © 2014 Milana Obradovic-Tomasev et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Obradovic-Tomasev, Milana
Popovic, Aleksandra
Vuckovic, Nada
Jovanovic, Mladen
Mixed Fungal Infection (Aspergillus, Mucor, and Candida) of Severe Hand Injury
title Mixed Fungal Infection (Aspergillus, Mucor, and Candida) of Severe Hand Injury
title_full Mixed Fungal Infection (Aspergillus, Mucor, and Candida) of Severe Hand Injury
title_fullStr Mixed Fungal Infection (Aspergillus, Mucor, and Candida) of Severe Hand Injury
title_full_unstemmed Mixed Fungal Infection (Aspergillus, Mucor, and Candida) of Severe Hand Injury
title_short Mixed Fungal Infection (Aspergillus, Mucor, and Candida) of Severe Hand Injury
title_sort mixed fungal infection (aspergillus, mucor, and candida) of severe hand injury
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978409/
https://www.ncbi.nlm.nih.gov/pubmed/24782933
http://dx.doi.org/10.1155/2014/954186
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