Dynamic pressurization induces transition of notochordal cells to a mature phenotype while retaining production of important patterning ligands from development

INTRODUCTION: Notochordal cells (NCs) pattern aneural and avascular intervertebral discs (IVDs), and their disappearance, is associated with onset of IVD degeneration. This study induced and characterized the maturation of nucleus pulposus (NP) tissue from a gelatinous NC-rich structure to a matrix-...

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Detalles Bibliográficos
Autores principales: Purmessur, Devina, Guterl, Clare C, Cho, Samuel K, Cornejo, Marisa C, Lam, Ying W, Ballif, Bryan A, Laudier, Damien M, Iatridis, James C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978427/
https://www.ncbi.nlm.nih.gov/pubmed/24427812
http://dx.doi.org/10.1186/ar4302

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