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Neuroprotective effects of donepezil against cholinergic depletion
INTRODUCTION: Intraparenchymal injections of the immunotoxin 192-IgG-saporin into medial septum and nucleus basalis magnocellularis causes a selective depletion of basal forebrain cholinergic neurons. Thus, it represents a valid model to mimic a key component of the cognitive deficits associated wit...
Autores principales: | Cutuli, Debora, De Bartolo, Paola, Caporali, Paola, Tartaglione, Anna Maria, Oddi, Diego, D’Amato, Francesca Romana, Nobili, Annalisa, D’Amelio, Marcello, Petrosini, Laura |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978431/ https://www.ncbi.nlm.nih.gov/pubmed/24401551 http://dx.doi.org/10.1186/alzrt215 |
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