A potential mechanism for extracellular matrix induction of breast cancer cell normality

Extracellular matrix proteins from embryonic mesenchyme have a normalizing effect on cancer cells in vitro and slow tumor growth in vivo. This concept is suggestive of a new method for controlling the growth and spread of existing cancer cells in situ and indicates the possibility that extracellular...

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Detalles Bibliográficos
Autores principales: Bruno, Robert D, Smith, Gilbert H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Viewpoint
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978454/
https://www.ncbi.nlm.nih.gov/pubmed/25927296
http://dx.doi.org/10.1186/bcr3617
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author Bruno, Robert D
Smith, Gilbert H
author_facet Bruno, Robert D
Smith, Gilbert H
author_sort Bruno, Robert D
collection PubMed
description Extracellular matrix proteins from embryonic mesenchyme have a normalizing effect on cancer cells in vitro and slow tumor growth in vivo. This concept is suggestive of a new method for controlling the growth and spread of existing cancer cells in situ and indicates the possibility that extracellular proteins and/or embryonic mesenchymal fibroblasts may represent a fertile subject for study of new anti-cancer treatments.
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spelling pubmed-39784542014-08-17 A potential mechanism for extracellular matrix induction of breast cancer cell normality Bruno, Robert D Smith, Gilbert H Breast Cancer Res Viewpoint Extracellular matrix proteins from embryonic mesenchyme have a normalizing effect on cancer cells in vitro and slow tumor growth in vivo. This concept is suggestive of a new method for controlling the growth and spread of existing cancer cells in situ and indicates the possibility that extracellular proteins and/or embryonic mesenchymal fibroblasts may represent a fertile subject for study of new anti-cancer treatments. BioMed Central 2014 2014-02-17 /pmc/articles/PMC3978454/ /pubmed/25927296 http://dx.doi.org/10.1186/bcr3617 Text en Copyright © 2014 Bruno and Smith; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 The licensee has exclusive rights to distribute this article, in any medium, for 6 months following its publication. After this time, the article is available under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Viewpoint
Bruno, Robert D
Smith, Gilbert H
A potential mechanism for extracellular matrix induction of breast cancer cell normality
title A potential mechanism for extracellular matrix induction of breast cancer cell normality
title_full A potential mechanism for extracellular matrix induction of breast cancer cell normality
title_fullStr A potential mechanism for extracellular matrix induction of breast cancer cell normality
title_full_unstemmed A potential mechanism for extracellular matrix induction of breast cancer cell normality
title_short A potential mechanism for extracellular matrix induction of breast cancer cell normality
title_sort potential mechanism for extracellular matrix induction of breast cancer cell normality
topic Viewpoint
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978454/
https://www.ncbi.nlm.nih.gov/pubmed/25927296
http://dx.doi.org/10.1186/bcr3617
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