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Mechanisms of Base Substitution Mutagenesis in Cancer Genomes

Cancer genome sequence data provide an invaluable resource for inferring the key mechanisms by which mutations arise in cancer cells, favoring their survival, proliferation and invasiveness. Here we examine recent advances in understanding the molecular mechanisms responsible for the predominant typ...

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Detalles Bibliográficos
Autores principales: Bacolla, Albino, Cooper, David N., Vasquez, Karen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978516/
https://www.ncbi.nlm.nih.gov/pubmed/24705290
http://dx.doi.org/10.3390/genes5010108