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GPR30 as an initiator of tamoxifen resistance in hormone-dependent breast cancer

INTRODUCTION: Tamoxifen is widely used to treat hormone-dependent breast cancer, but its therapeutic benefit is limited by the development of drug resistance. Here, we investigated the role of estrogen G-protein coupled receptor 30 (GPR30) on Tamoxifen resistance in breast cancer. METHODS: Primary t...

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Detalles Bibliográficos
Autores principales: Mo, Zhiqiang, Liu, Manran, Yang, Fangfang, Luo, Haojun, Li, Zhenhua, Tu, Gang, Yang, Guanglun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978564/
https://www.ncbi.nlm.nih.gov/pubmed/24289103
http://dx.doi.org/10.1186/bcr3581