Identifying driver mutations in sequenced cancer genomes: computational approaches to enable precision medicine

High-throughput DNA sequencing is revolutionizing the study of cancer and enabling the measurement of the somatic mutations that drive cancer development. However, the resulting sequencing datasets are large and complex, obscuring the clinically important mutations in a background of errors, noise,...

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Detalles Bibliográficos
Autores principales: Raphael, Benjamin J, Dobson, Jason R, Oesper, Layla, Vandin, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978567/
https://www.ncbi.nlm.nih.gov/pubmed/24479672
http://dx.doi.org/10.1186/gm524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978567/
https://www.ncbi.nlm.nih.gov/pubmed/24479672
http://dx.doi.org/10.1186/gm524

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