Prolactin-Stat5 signaling in breast cancer is potently disrupted by acidosis within the tumor microenvironment

INTRODUCTION: Emerging evidence in estrogen receptor-positive breast cancer supports the notion that prolactin-Stat5 signaling promotes survival and maintenance of differentiated luminal cells, and loss of nuclear tyrosine phosphorylated Stat5 (Nuc-pYStat5) in clinical breast cancer is associated wi...

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Detalles Bibliográficos
Autores principales: Yang, Ning, Liu, Chengbao, Peck, Amy R, Girondo, Melanie A, Yanac, Alicia F, Tran, Thai H, Utama, Fransiscus E, Tanaka, Takemi, Freydin, Boris, Chervoneva, Inna, Hyslop, Terry, Kovatich, Albert J, Hooke, Jeffrey A, Shriver, Craig D, Rui, Hallgeir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978581/
https://www.ncbi.nlm.nih.gov/pubmed/24004716
http://dx.doi.org/10.1186/bcr3467

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