Par-4 prevents breast cancer recurrence

Therapy resistance and disease recurrence are two of the most challenging aspects in breast cancer treatment. A recent article in Cancer Cell makes a significant contribution toward a better understanding of this therapeutic problem by establishing downregulation of the tumor suppressor Par-4 as the...

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Detalles Bibliográficos
Autores principales: Hebbar, Nikhil, Shrestha-Bhattarai, Tripti, Rangnekar, Vivek M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Viewpoint
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978615/
https://www.ncbi.nlm.nih.gov/pubmed/24164776
http://dx.doi.org/10.1186/bcr3562
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author Hebbar, Nikhil
Shrestha-Bhattarai, Tripti
Rangnekar, Vivek M
author_facet Hebbar, Nikhil
Shrestha-Bhattarai, Tripti
Rangnekar, Vivek M
author_sort Hebbar, Nikhil
collection PubMed
description Therapy resistance and disease recurrence are two of the most challenging aspects in breast cancer treatment. A recent article in Cancer Cell makes a significant contribution toward a better understanding of this therapeutic problem by establishing downregulation of the tumor suppressor Par-4 as the primary determinant of breast cancer recurrence. This viewpoint brings forth the importance of their findings and its implications on future research and therapy.
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spelling pubmed-39786152014-04-25 Par-4 prevents breast cancer recurrence Hebbar, Nikhil Shrestha-Bhattarai, Tripti Rangnekar, Vivek M Breast Cancer Res Viewpoint Therapy resistance and disease recurrence are two of the most challenging aspects in breast cancer treatment. A recent article in Cancer Cell makes a significant contribution toward a better understanding of this therapeutic problem by establishing downregulation of the tumor suppressor Par-4 as the primary determinant of breast cancer recurrence. This viewpoint brings forth the importance of their findings and its implications on future research and therapy. BioMed Central 2013 2013-10-25 /pmc/articles/PMC3978615/ /pubmed/24164776 http://dx.doi.org/10.1186/bcr3562 Text en Copyright © 2013 BioMed Central Ltd.
spellingShingle Viewpoint
Hebbar, Nikhil
Shrestha-Bhattarai, Tripti
Rangnekar, Vivek M
Par-4 prevents breast cancer recurrence
title Par-4 prevents breast cancer recurrence
title_full Par-4 prevents breast cancer recurrence
title_fullStr Par-4 prevents breast cancer recurrence
title_full_unstemmed Par-4 prevents breast cancer recurrence
title_short Par-4 prevents breast cancer recurrence
title_sort par-4 prevents breast cancer recurrence
topic Viewpoint
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978615/
https://www.ncbi.nlm.nih.gov/pubmed/24164776
http://dx.doi.org/10.1186/bcr3562
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AT shresthabhattaraitripti par4preventsbreastcancerrecurrence
AT rangnekarvivekm par4preventsbreastcancerrecurrence

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