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Serum nitrated nucleosome levels in patients with systemic lupus erythematosus: a retrospective longitudinal cohort study
INTRODUCTION: Circulating nucleosomes released from apoptotic cells are important in the pathogenesis of systemic lupus erythematosus (SLE). Both nucleosomes and anti-nucleosome antibodies are deposited in inflamed tissues in patients with SLE. Active inflammation promotes nitration of tyrosine resi...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978622/ https://www.ncbi.nlm.nih.gov/pubmed/24502558 http://dx.doi.org/10.1186/ar4477 |