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Transforming growth factor-β signalling controls human breast cancer metastasis in a zebrafish xenograft model

INTRODUCTION: The transforming growth factor beta (TGF-β) signalling pathway is known to control human breast cancer invasion and metastasis. We demonstrate that the zebrafish xenograft assay is a robust and dependable animal model for examining the role of pharmacological modulators and genetic per...

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Detalles Bibliográficos
Autores principales: Drabsch, Yvette, He, Shuning, Zhang, Long, Snaar-Jagalska, B Ewa, ten Dijke, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978640/
https://www.ncbi.nlm.nih.gov/pubmed/24196484
http://dx.doi.org/10.1186/bcr3573

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