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Transforming growth factor-β signalling controls human breast cancer metastasis in a zebrafish xenograft model
INTRODUCTION: The transforming growth factor beta (TGF-β) signalling pathway is known to control human breast cancer invasion and metastasis. We demonstrate that the zebrafish xenograft assay is a robust and dependable animal model for examining the role of pharmacological modulators and genetic per...
Autores principales: | Drabsch, Yvette, He, Shuning, Zhang, Long, Snaar-Jagalska, B Ewa, ten Dijke, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978640/ https://www.ncbi.nlm.nih.gov/pubmed/24196484 http://dx.doi.org/10.1186/bcr3573 |
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