A mitochondria-targeted mass spectrometry probe to detect glyoxals: implications for diabetes()

The glycation of protein and nucleic acids that occurs as a consequence of hyperglycemia disrupts cell function and contributes to many pathologies, including those associated with diabetes and aging. Intracellular glycation occurs after the generation of the reactive 1,2-dicarbonyls methylglyoxal a...

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Detalles Bibliográficos
Autores principales: Pun, Pamela Boon Li, Logan, Angela, Darley-Usmar, Victor, Chacko, Balu, Johnson, Michelle S., Huang, Guang W., Rogatti, Sebastian, Prime, Tracy A., Methner, Carmen, Krieg, Thomas, Fearnley, Ian M., Larsen, Lesley, Larsen, David S., Menger, Katja E., Collins, Yvonne, James, Andrew M., Kumar, G.D. Kishore, Hartley, Richard C., Smith, Robin A.J., Murphy, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2014
Materias:
Original Contribution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978666/
https://www.ncbi.nlm.nih.gov/pubmed/24316194
http://dx.doi.org/10.1016/j.freeradbiomed.2013.11.025

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