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Nanoparticulate flurbiprofen reduces amyloid-β(42) generation in an in vitro blood–brain barrier model
INTRODUCTION: The amyloid-β(42) (Aβ(42)) peptide plays a crucial role in the pathogenesis of Alzheimer’s disease (AD), the most common neurodegenerative disorder affecting the elderly. Over the past years, several approaches and compounds developed for the treatment of AD have failed in clinical stu...
Autores principales: | Meister, Sabrina, Zlatev, Iavor, Stab, Julia, Docter, Dominic, Baches, Sandra, Stauber, Roland H, Deutsch, Mordechai, Schmidt, Reinhold, Ropele, Stefan, Windisch, Manfred, Langer, Klaus, Wagner, Sylvia, von Briesen, Hagen, Weggen, Sascha, Pietrzik, Claus U |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978673/ https://www.ncbi.nlm.nih.gov/pubmed/24280275 http://dx.doi.org/10.1186/alzrt225 |
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