Nanoparticulate flurbiprofen reduces amyloid-β(42) generation in an in vitro blood–brain barrier model

INTRODUCTION: The amyloid-β(42) (Aβ(42)) peptide plays a crucial role in the pathogenesis of Alzheimer’s disease (AD), the most common neurodegenerative disorder affecting the elderly. Over the past years, several approaches and compounds developed for the treatment of AD have failed in clinical stu...

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Detalles Bibliográficos
Autores principales: Meister, Sabrina, Zlatev, Iavor, Stab, Julia, Docter, Dominic, Baches, Sandra, Stauber, Roland H, Deutsch, Mordechai, Schmidt, Reinhold, Ropele, Stefan, Windisch, Manfred, Langer, Klaus, Wagner, Sylvia, von Briesen, Hagen, Weggen, Sascha, Pietrzik, Claus U
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978673/
https://www.ncbi.nlm.nih.gov/pubmed/24280275
http://dx.doi.org/10.1186/alzrt225

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