Cargando…

Hypercholesterolemia boosts joint destruction in chronic arthritis. An experimental model aggravated by foam macrophage infiltration

OBJECTIVE: The aim of this study was to determine whether hypercholesterolemia increases articular damage in a rabbit model of chronic arthritis. METHODS: Hypercholesterolemia was induced in 18 rabbits by administrating a high-fat diet (HFD). Fifteen rabbits were fed normal chow as controls. Chronic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Prieto-Potín, I, Roman-Blas, JA, Martínez-Calatrava, MJ, Gómez, R, Largo, R, Herrero-Beaumont, Gabriel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978700/ https://www.ncbi.nlm.nih.gov/pubmed/23941259 http://dx.doi.org/10.1186/ar4261

Ejemplares similares

RANKL synthesized by articular chondrocytes contributes to juxta-articular bone loss in chronic arthritis
por: Martínez-Calatrava, Maria J, et al.
Publicado: (2012)

Increased synovial lipodystrophy induced by high fat diet aggravates synovitis in experimental osteoarthritis
por: Larrañaga-Vera, Ane, et al.
Publicado: (2017)

Characterization of multinucleated giant cells in synovium and subchondral bone in knee osteoarthritis and rheumatoid arthritis
por: Prieto-Potin, Iván, et al.
Publicado: (2015)

Disorganization of chondrocyte columns in the growth plate does not aggravate experimental osteoarthritis in mice
por: Lamuedra, Ana, et al.
Publicado: (2020)

Mediators and Patterns of Muscle Loss in Chronic Systemic Inflammation
por: Pérez-Baos, Sandra, et al.
Publicado: (2018)

Subchondral bone microstructural damage by increased remodelling aggravates experimental osteoarthritis preceded by osteoporosis
por: Bellido, Miriam, et al.
Publicado: (2010)

Modulation of the Inflammatory Process by Hypercholesterolemia in Osteoarthritis
por: Villalvilla, Amanda, et al.
Publicado: (2020)

Subchondral bone remodelling and osteoarthritis
por: Román-Blas, Jorge A, et al.
Publicado: (2012)

Osteoarthritis associated with estrogen deficiency
por: Roman-Blas, Jorge A, et al.
Publicado: (2009)

Compensatory anabolic signaling in the sarcopenia of experimental chronic arthritis
por: Little, Robert D., et al.
Publicado: (2017)

Setting up distinctive outcome measures for each osteoarthritis phenotype
por: Roman-Blas, Jorge A., et al.
Publicado: (2020)

ATP transporters in the joints
por: Larrañaga-Vera, Ane, et al.
Publicado: (2021)

Transcriptional profiling of foam cells in response to hypercholesterolemia
por: Goo, Young-Hwa, et al.
Publicado: (2016)

Baicalein Neutralizes Hypercholesterolemia-Induced Aggravation of Oxidative Injury in Rats
por: AlSaad, Abdulaziz MS, et al.
Publicado: (2020)

Transgenic mice over-expressing carbonic anhydrase I showed aggravated joint inflammation and tissue destruction
por: Zheng, Yabing, et al.
Publicado: (2012)

Reduced skeletal muscle independently predicts 1-year aggravated joint destruction in patients with rheumatoid arthritis
por: Lin, Jian-Zi, et al.
Publicado: (2020)

Interleukin-7-aggravated joint inflammation and tissue destruction in collagen-induced arthritis is associated with T-cell and B-cell activation
por: Hartgring, Sarita AY, et al.
Publicado: (2012)

Mechanical unloading aggravates bone destruction and tumor expansion in myeloma
por: Tanimoto, Kotaro, et al.
Publicado: (2021)

Targeting subchondral bone in osteoporotic osteoarthritis
por: Roman-Blas, Jorge A, et al.
Publicado: (2014)

Investigation of the Foam Development Stages by Non-Destructive Testing Technology Using the Freeze Foaming Process
por: Maier, Johanna, et al.
Publicado: (2018)

Targeting ApoC3 Paradoxically Aggravates Atherosclerosis in Hamsters With Severe Refractory Hypercholesterolemia
por: Xu, Yitong, et al.
Publicado: (2022)

IDH1 Promotes Foam Cell Formation by Aggravating Macrophage Ferroptosis
por: Li, Ben, et al.
Publicado: (2022)

Lipid Transport and Metabolism in Healthy and Osteoarthritic Cartilage
por: Villalvilla, Amanda, et al.
Publicado: (2013)

Proteinases in the joint: clinical relevance of proteinases in joint destruction
por: Rengel, Yvonne, et al.
Publicado: (2007)

Osteoclasts are essential for TNF-mediated joint destruction
por: Redlich, KR, et al.
Publicado: (2002)

Essential Role for the C5a Receptor in Regulating the Effector Phase of Synovial Infiltration and Joint Destruction in Experimental Arthritis
por: Grant, Ethan P., et al.
Publicado: (2002)

Typhoon-boosted biogenic emission aggravates cross-regional ozone pollution in China
por: Wang, Nan, et al.
Publicado: (2022)

Tenofovir Modulates Semaphorin 4D Signaling and Regulates Bone Homeostasis, Which Can Be Counteracted by Dipyridamole and Adenosine A2A Receptor
por: Llamas-Granda, Patricia, et al.
Publicado: (2021)

High glucose-induced intestinal epithelial barrier damage is aggravated by syndecan-1 destruction and heparanase overexpression
por: Qing, Qing, et al.
Publicado: (2015)

The adipokine lipocalin-2 in the context of the osteoarthritic osteochondral junction
por: Villalvilla, Amanda, et al.
Publicado: (2016)

Corrigendum: The adipokine lipocalin-2 in the context of the osteoarthritic osteochondral junction
por: Villalvilla, Amanda, et al.
Publicado: (2016)

Simvastatin therapy attenuates memory deficits that associate with brain monocyte infiltration in chronic hypercholesterolemia
por: Don-Doncow, Nicholas, et al.
Publicado: (2021)

A possible cause of joint destruction in septic arthritis
por: Krieg, Arthur M
Publicado: (1999)

Diabetes-induced osteoarthritis: role of hyperglycemia in joint destruction
por: Mendes, Alexandrina F, et al.
Publicado: (2015)

Role of LIGHT in the pathogenesis of joint destruction in rheumatoid arthritis
por: Sabokbar, Afsie, et al.
Publicado: (2017)

Macrophages derived from infiltrating monocytes mediate autoimmune myelin destruction
por: Heneka, Michael T.
Publicado: (2014)

Targeted Panel Sequencing will Boost Detection of Genetic Backgrounds of Familial Hypercholesterolemia in the World's Most Populous Country
por: Tada, Hayato, et al.
Publicado: (2020)

Obesity-Related Gut Microbiota Aggravates Alveolar Bone Destruction in Experimental Periodontitis through Elevation of Uric Acid
por: Sato, Keisuke, et al.
Publicado: (2021)

Genetics of Hypercholesterolemia: Comparison Between Familial Hypercholesterolemia and Hypercholesterolemia Nonrelated to LDL Receptor
por: Jarauta, Estíbaliz, et al.
Publicado: (2020)

Improving the Strength of ZTA Foams with Different Strategies: Immersion Infiltration and Recoating
por: Chen, Xiaodong, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_364aekjukiapcd5gaqbr0i69fm