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NFAT3 and TGF-β/SMAD3 regulate the expression of miR-140 in osteoarthritis

INTRODUCTION: MicroRNAs (miRNAs) down-regulate their target genes. The intronic miR-140, present in the WW domain containing E3 ubiquitin protein ligase 2 (WWP2) gene, decreases the expression of genes that play detrimental roles in osteoarthritis (OA). As the expression level of miR-140 is signific...

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Detalles Bibliográficos
Autores principales:	Tardif, Ginette, Pelletier, Jean-Pierre, Fahmi, Hassan, Hum, David, Zhang, Yue, Kapoor, Mohit, Martel-Pelletier, Johanne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978709/ https://www.ncbi.nlm.nih.gov/pubmed/24257415 http://dx.doi.org/10.1186/ar4387

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