Cdc42 overexpression induces hyperbranching in the developing mammary gland by enhancing cell migration

INTRODUCTION: The Rho GTPase Cdc42 is overexpressed and hyperactivated in breast tumors compared to normal breast tissue. Cdc42 regulates key processes that are critical for mammary gland morphogenesis and become disrupted during the development, progression, and metastasis of breast cancer. However...

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Detalles Bibliográficos
Autores principales: Bray, Kristi, Gillette, Melissa, Young, Jeanette, Loughran, Elizabeth, Hwang, Melissa, Sears, James Cooper, Vargo-Gogola, Tracy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978759/
https://www.ncbi.nlm.nih.gov/pubmed/24074261
http://dx.doi.org/10.1186/bcr3487

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