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Evidence for impaired amyloid β clearance in Alzheimer's disease

Alzheimer's disease (AD) is a common neurodegenerative disease characterized by the accumulation of extracellular plaques and intracellular tangles. Recent studies support the hypothesis that the accumulation of amyloid beta (Aβ) peptide within the brain arises from an imbalance of the producti...

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Detalles Bibliográficos
Autores principales: Wildsmith, Kristin R, Holley, Monica, Savage, Julie C, Skerrett, Rebecca, Landreth, Gary E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978761/
https://www.ncbi.nlm.nih.gov/pubmed/23849219
http://dx.doi.org/10.1186/alzrt187

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