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Structural basis for the assembly of the mitotic motor Kinesin-5 into bipolar tetramers

Chromosome segregation during mitosis depends upon Kinesin-5 motors, which display a conserved, bipolar homotetrameric organization consisting of two motor dimers at opposite ends of a central rod. Kinesin-5 motors crosslink adjacent microtubules to drive or constrain their sliding apart, but the st...

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Detalles Bibliográficos
Autores principales:	Scholey, Jessica E, Nithianantham, Stanley, Scholey, Jonathan M, Al-Bassam, Jawdat
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2014
Materias:	Biophysics and Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978770/ https://www.ncbi.nlm.nih.gov/pubmed/24714498 http://dx.doi.org/10.7554/eLife.02217

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