Increased physical activity severely induces osteoarthritic changes in knee joints with papain induced sulfate-glycosaminoglycan depleted cartilage

INTRODUCTION: Articular cartilage needs sulfated-glycosaminoglycans (sGAGs) to withstand high pressures while mechanically loaded. Chondrocyte sGAG synthesis is regulated by exposure to compressive forces. Moderate physical exercise is known to improve cartilage sGAG content and might protect agains...

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Detalles Bibliográficos
Autores principales: Siebelt, Michiel, Groen, Harald C, Koelewijn, Stuart J, de Blois, Erik, Sandker, Marjan, Waarsing, Jan H, Müller, Cristina, van Osch, Gerjo JVM, de Jong, Marion, Weinans, Harrie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978821/
https://www.ncbi.nlm.nih.gov/pubmed/24472689
http://dx.doi.org/10.1186/ar4461

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