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A mammosphere formation RNAi screen reveals that ATG4A promotes a breast cancer stem-like phenotype

INTRODUCTION: Breast cancer stem cells are suspected to be responsible for tumour recurrence, metastasis formation as well as chemoresistance. Consequently, great efforts have been made to understand the molecular mechanisms underlying cancer stem cell maintenance. In order to study these rare cells...

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Detalles Bibliográficos
Autores principales: Wolf, Jonas, Dewi, Dyah Laksmi, Fredebohm, Johannes, Müller-Decker, Karin, Flechtenmacher, Christa, Hoheisel, Jörg D, Boettcher, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978845/
https://www.ncbi.nlm.nih.gov/pubmed/24229464
http://dx.doi.org/10.1186/bcr3576