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A mammosphere formation RNAi screen reveals that ATG4A promotes a breast cancer stem-like phenotype
INTRODUCTION: Breast cancer stem cells are suspected to be responsible for tumour recurrence, metastasis formation as well as chemoresistance. Consequently, great efforts have been made to understand the molecular mechanisms underlying cancer stem cell maintenance. In order to study these rare cells...
Autores principales: | Wolf, Jonas, Dewi, Dyah Laksmi, Fredebohm, Johannes, Müller-Decker, Karin, Flechtenmacher, Christa, Hoheisel, Jörg D, Boettcher, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978845/ https://www.ncbi.nlm.nih.gov/pubmed/24229464 http://dx.doi.org/10.1186/bcr3576 |
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