Cargando…

Low-density lipoprotein receptor–related protein 5 governs Wnt-mediated osteoarthritic cartilage destruction

INTRODUCTION: Wnt ligands bind to low-density lipoprotein receptor–related protein (LRP) 5 or 6, triggering a cascade of downstream events that include β-catenin signaling. Here we explored the roles of LRP5 in interleukin 1β (IL-1β)- or Wnt-mediated osteoarthritic (OA) cartilage destruction in mice...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shin, Youngnim, Huh, Yun Hyun, Kim, Kieun, Kim, Suyeon, Park, Ka Hyon, Koh, Jeong-Tae, Chun, Jang-Soo, Ryu, Je-Hwang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978879/ https://www.ncbi.nlm.nih.gov/pubmed/24479426 http://dx.doi.org/10.1186/ar4466

Ejemplares similares

Inhibition of BATF/JUN transcriptional activity protects against osteoarthritic cartilage destruction
por: Rhee, Jinseol, et al.
Publicado: (2017)

Hypoxia-inducible factor-2α regulates Fas-mediated chondrocyte apoptosis during osteoarthritic cartilage destruction
por: Ryu, J-H, et al.
Publicado: (2012)

NF-κB Signaling Pathways in Osteoarthritic Cartilage Destruction
por: Choi, Moon-Chang, et al.
Publicado: (2019)

Cirsium japonicum var. maackii and apigenin block Hif‐2α‐induced osteoarthritic cartilage destruction
por: Cho, Chanmi, et al.
Publicado: (2019)

Mithramycin A Alleviates Osteoarthritic Cartilage Destruction by Inhibiting HIF-2α Expression
por: Choi, Moon-Chang, et al.
Publicado: (2018)

Characteristic Markers of the WNT Signaling Pathways Are Differentially Expressed in Osteoarthritic Cartilage
por: Thorfve, A., et al.
Publicado: (2012)

Up-regulation of P21-activated kinase 1 in osteoarthritis chondrocytes is responsible for osteoarthritic cartilage destruction
por: Ma, Wanli, et al.
Publicado: (2020)

The Role of Autophagy in Osteoarthritic Cartilage
por: Kao, Wei-Chun, et al.
Publicado: (2022)

Superoxide dismutase activity is significantly lower in end-stage osteoarthritic cartilage than non-osteoarthritic cartilage
por: Koike, Masato, et al.
Publicado: (2018)

The role of aggrecan in normal and osteoarthritic cartilage
por: Roughley, Peter J, et al.
Publicado: (2014)

Avenanthramide C as a novel candidate to alleviate osteoarthritic pathogenesis
por: Tran, Thanh-Tam, et al.
Publicado: (2021)

Lipid Transport and Metabolism in Healthy and Osteoarthritic Cartilage
por: Villalvilla, Amanda, et al.
Publicado: (2013)

Heparan sulfate functions are altered in the osteoarthritic cartilage
por: Shamdani, Sara, et al.
Publicado: (2020)

Wnt-β-catenin signaling pathway inhibition by sclerostin may protect against degradation in healthy but not osteoarthritic cartilage
por: Wu, Jiang, et al.
Publicado: (2017)

Elevation of α-1,3 fucosylation promotes the binding ability of TNFR1 to TNF-α and contributes to osteoarthritic cartilage destruction and apoptosis
por: Yu, Hanjie, et al.
Publicado: (2022)

MRI-based hip cartilage measures in osteoarthritic and non-osteoarthritic individuals: a systematic review
por: Aguilar, Hector N, et al.
Publicado: (2017)

Tankyrase inhibition preserves osteoarthritic cartilage by coordinating cartilage matrix anabolism via effects on SOX9 PARylation
por: Kim, Sukyeong, et al.
Publicado: (2019)

Cartilage repair in osteoarthritic patients: utopia or real opportunity?
por: Henrotin, Yves, et al.
Publicado: (2009)

Arthroscopic cartilage regeneration facilitating procedure for osteoarthritic knee
por: Lyu, Shaw-Ruey, et al.
Publicado: (2012)

Toll-like receptors in human chondrocytes and osteoarthritic cartilage
por: Sillat, Tarvo, et al.
Publicado: (2013)

Regulation of Cholesterol Homeostasis by Hedgehog Signaling in Osteoarthritic Cartilage
por: Ali, Shabana Amanda, et al.
Publicado: (2016)

The role of TNFRSF11B in development of osteoarthritic cartilage
por: Rodríguez Ruiz, Alejandro, et al.
Publicado: (2021)

Remodeling Osteoarthritic Articular Cartilage under Hypoxic Conditions
por: Mohd Yunus, Mohd Heikal, et al.
Publicado: (2022)

3′‐Sialyllactose protects against osteoarthritic development by facilitating cartilage homeostasis
por: Jeon, Jimin, et al.
Publicado: (2017)

New insight on the subchondral bone and cartilage functional unit: Bone mineral density and cartilage thickness are spatially correlated in non-osteoarthritic femoral condyles
por: Babel, Hugo, et al.
Publicado: (2020)

Silicone Stent Placement for Primary Tracheal Amyloidosis Accompanied by Cartilage Destruction
por: Ryu, Duck Hyun, et al.
Publicado: (2014)

Quantitative imaging of excised osteoarthritic cartilage using spectral CT
por: Rajendran, Kishore, et al.
Publicado: (2017)

Repression of anti-proliferative factor Tob1 in osteoarthritic cartilage
por: Gebauer, Mathias, et al.
Publicado: (2005)

Histochemistry as a Unique Approach for Investigating Normal and Osteoarthritic Cartilage
por: Musumeci, G., et al.
Publicado: (2014)

Hyaluronic Acid Influence on Normal and Osteoarthritic Tissue-Engineered Cartilage
por: Hemmati-Sadeghi, Shabnam, et al.
Publicado: (2018)

Mathematical modelling of cytokines, MMPs and fibronectin fragments in osteoarthritic cartilage
por: Baker, Michelle, et al.
Publicado: (2017)

Osteoarthritic Subchondral Bone Release Exosomes That Promote Cartilage Degeneration
por: Wu, Xiaoxin, et al.
Publicado: (2021)

Chondrocytes From Osteoarthritic and Chondrocalcinosis Cartilage Represent Different Phenotypes
por: Meyer, Franziska, et al.
Publicado: (2021)

Advances in Research on the Regulatory Roles of lncRNAs in Osteoarthritic Cartilage
por: Wu, Jiaqi, et al.
Publicado: (2023)

Analysis of RNA Polyadenylation in Healthy and Osteoarthritic Human Articular Cartilage
por: Winstanley-Zarach, Phaedra, et al.
Publicado: (2023)

Analysis of proteins released from osteoarthritic cartilage by compressive loading
por: Tsuno, Hirotaka, et al.
Publicado: (2023)

Paracrine pathways of cartilage destruction in osteoarthritis
por: Abramson, S, et al.
Publicado: (2003)

Cartilage destruction by matrix degradation products
por: Yasuda, Tadashi
Publicado: (2006)

Low Levels of Low-Density Lipoprotein Cholesterol and Mortality Outcomes in Non-Statin Users
por: Sung, Ki-Chul, et al.
Publicado: (2019)

Tenascin-C induces inflammatory mediators and matrix degradation in osteoarthritic cartilage
por: Patel, Lisha, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_kl4ekgfnomtqhqsvfqmjl5go8n