B lymphocytes and B-cell activating factor promote collagen and profibrotic markers expression by dermal fibroblasts in systemic sclerosis

INTRODUCTION: B lymphocytes might play a pathogenic role in dermal fibrosis in systemic sclerosis (SSc). B-cell activating factor (BAFF), a key cytokine for B-cell activation, is increased in the serum and the skin of patients with SSc. However, the ability of B cells directly to stimulate dermal fi...

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Detalles Bibliográficos
Autores principales: François, Antoine, Chatelus, Emmanuel, Wachsmann, Dominique, Sibilia, Jean, Bahram, Seiamak, Alsaleh, Ghada, Gottenberg, Jacques-Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978899/
https://www.ncbi.nlm.nih.gov/pubmed/24289101
http://dx.doi.org/10.1186/ar4352

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