Cargando…
Impact of extracellular matrix derived from osteoarthritis subchondral bone osteoblasts on osteocytes: role of integrinβ1 and focal adhesion kinase signaling cues
INTRODUCTION: Our recent study indicated that subchondral bone pathogenesis in osteoarthritis (OA) is associated with osteocyte morphology and phenotypic abnormalities. However, the mechanism underlying this abnormality needs to be identified. In this study we investigated the effect of extracellula...
Autores principales: | Prasadam, Indira, Farnaghi, Saba, Feng, Jian Q, Gu, Wenyi, Perry, Samuel, Crawford, Ross, Xiao, Yin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978998/ https://www.ncbi.nlm.nih.gov/pubmed/24289792 http://dx.doi.org/10.1186/ar4333 |
Ejemplares similares
-
Phenotypic Characterization of Osteoarthritic Osteocytes from the Sclerotic Zones: A Possible Pathological Role in Subchondral Bone Sclerosis
por: Jaiprakash, Anjali, et al.
Publicado: (2012) -
Identification of mechanics-responsive osteocyte signature in osteoarthritis subchondral bone
por: Zhou, Jun, et al.
Publicado: (2022) -
Osteoarthritic Subchondral Bone Release Exosomes That Promote Cartilage Degeneration
por: Wu, Xiaoxin, et al.
Publicado: (2021) -
Inflammatory macrophages interrupt osteocyte maturation and mineralization via regulating the Notch signaling pathway
por: Wang, Shengfang, et al.
Publicado: (2022) -
Characterization of nano-structural and nano-mechanical properties of osteoarthritic subchondral bone
por: Zuo, Qiliang, et al.
Publicado: (2016)