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Direct repression of MYB by ZEB1 suppresses proliferation and epithelial gene expression during epithelial-to-mesenchymal transition of breast cancer cells

INTRODUCTION: Epithelial-to-mesenchymal transition (EMT) promotes cell migration and is important in metastasis. Cellular proliferation is often downregulated during EMT, and the reverse transition (MET) in metastases appears to be required for restoration of proliferation in secondary tumors. We st...

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Detalles Bibliográficos
Autores principales: Hugo, Honor J, Pereira, Lloyd, Suryadinata, Randy, Drabsch, Yvette, Gonda, Thomas J, Gunasinghe, N P A Devika, Pinto, Cletus, Soo, Eliza TL, van Denderen, Bryce JW, Hill, Prue, Ramsay, Robert G, Sarcevic, Boris, Newgreen, Donald F, Thompson, Erik W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979034/
https://www.ncbi.nlm.nih.gov/pubmed/24283570
http://dx.doi.org/10.1186/bcr3580