Cargando…
Direct repression of MYB by ZEB1 suppresses proliferation and epithelial gene expression during epithelial-to-mesenchymal transition of breast cancer cells
INTRODUCTION: Epithelial-to-mesenchymal transition (EMT) promotes cell migration and is important in metastasis. Cellular proliferation is often downregulated during EMT, and the reverse transition (MET) in metastases appears to be required for restoration of proliferation in secondary tumors. We st...
Autores principales: | Hugo, Honor J, Pereira, Lloyd, Suryadinata, Randy, Drabsch, Yvette, Gonda, Thomas J, Gunasinghe, N P A Devika, Pinto, Cletus, Soo, Eliza TL, van Denderen, Bryce JW, Hill, Prue, Ramsay, Robert G, Sarcevic, Boris, Newgreen, Donald F, Thompson, Erik W |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979034/ https://www.ncbi.nlm.nih.gov/pubmed/24283570 http://dx.doi.org/10.1186/bcr3580 |
Ejemplares similares
-
MYB suppresses differentiation and apoptosis of human breast cancer cells
por: Drabsch, Yvette, et al.
Publicado: (2010) -
Estrogen receptor-α recruits P-TEFb to overcome transcriptional pausing in intron 1 of the MYB gene
por: Mitra, Partha, et al.
Publicado: (2012) -
Mechanisms of Generating Polyubiquitin Chains of Different Topology
por: Suryadinata, Randy, et al.
Publicado: (2014) -
SIP1/ZEB2 induces EMT by repressing genes of different epithelial cell–cell junctions
por: Vandewalle, Cindy, et al.
Publicado: (2005) -
p53 regulates epithelial–mesenchymal transition through microRNAs targeting ZEB1 and ZEB2
por: Kim, Taewan, et al.
Publicado: (2011)