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Potential synergy between tau aggregation inhibitors and tau chaperone modulators
Tau is a soluble, microtubule-associated protein known to aberrantly form amyloid-positive aggregates. This pathology is characteristic for more than 15 neuropathies, the most common of which is Alzheimer’s disease. Finding therapeutics to reverse or remove this non-native tau state is of great inte...
Autores principales: | Blair, Laura J, Zhang, Bo, Dickey, Chad A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979086/ https://www.ncbi.nlm.nih.gov/pubmed/24041111 http://dx.doi.org/10.1186/alzrt207 |
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