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Potential synergy between tau aggregation inhibitors and tau chaperone modulators

Tau is a soluble, microtubule-associated protein known to aberrantly form amyloid-positive aggregates. This pathology is characteristic for more than 15 neuropathies, the most common of which is Alzheimer’s disease. Finding therapeutics to reverse or remove this non-native tau state is of great inte...

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Detalles Bibliográficos
Autores principales: Blair, Laura J, Zhang, Bo, Dickey, Chad A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979086/
https://www.ncbi.nlm.nih.gov/pubmed/24041111
http://dx.doi.org/10.1186/alzrt207

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