Pregnancy offers new insights into mechanisms of breast cancer risk and resistance

Pregnancy induces long-lasting changes in gene expression that are associated with a reduction in breast cancer risk. Although several mechanisms have been proposed to mediate the reduction in breast cancer risk among parous women, recent studies focus attention on progenitor cells as major targets....

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Detalles Bibliográficos
Autores principales: Jerry, D Joseph, Makari-Judson, Grace, Crisi, Giovanna M, Dunphy, Karen A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Viewpoint
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979118/
https://www.ncbi.nlm.nih.gov/pubmed/24060354
http://dx.doi.org/10.1186/bcr3482
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author Jerry, D Joseph
Makari-Judson, Grace
Crisi, Giovanna M
Dunphy, Karen A
author_facet Jerry, D Joseph
Makari-Judson, Grace
Crisi, Giovanna M
Dunphy, Karen A
author_sort Jerry, D Joseph
collection PubMed
description Pregnancy induces long-lasting changes in gene expression that are associated with a reduction in breast cancer risk. Although several mechanisms have been proposed to mediate the reduction in breast cancer risk among parous women, recent studies focus attention on progenitor cells as major targets. The results suggest new biomarkers that may improve risk prediction and provide endpoints for assessment of clinical responses to prophylactic therapies.
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spelling pubmed-39791182014-04-08 Pregnancy offers new insights into mechanisms of breast cancer risk and resistance Jerry, D Joseph Makari-Judson, Grace Crisi, Giovanna M Dunphy, Karen A Breast Cancer Res Viewpoint Pregnancy induces long-lasting changes in gene expression that are associated with a reduction in breast cancer risk. Although several mechanisms have been proposed to mediate the reduction in breast cancer risk among parous women, recent studies focus attention on progenitor cells as major targets. The results suggest new biomarkers that may improve risk prediction and provide endpoints for assessment of clinical responses to prophylactic therapies. BioMed Central 2013 2013-09-24 /pmc/articles/PMC3979118/ /pubmed/24060354 http://dx.doi.org/10.1186/bcr3482 Text en Copyright © 2013 BioMed Central Ltd.
spellingShingle Viewpoint
Jerry, D Joseph
Makari-Judson, Grace
Crisi, Giovanna M
Dunphy, Karen A
Pregnancy offers new insights into mechanisms of breast cancer risk and resistance
title Pregnancy offers new insights into mechanisms of breast cancer risk and resistance
title_full Pregnancy offers new insights into mechanisms of breast cancer risk and resistance
title_fullStr Pregnancy offers new insights into mechanisms of breast cancer risk and resistance
title_full_unstemmed Pregnancy offers new insights into mechanisms of breast cancer risk and resistance
title_short Pregnancy offers new insights into mechanisms of breast cancer risk and resistance
title_sort pregnancy offers new insights into mechanisms of breast cancer risk and resistance
topic Viewpoint
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979118/
https://www.ncbi.nlm.nih.gov/pubmed/24060354
http://dx.doi.org/10.1186/bcr3482
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AT dunphykarena pregnancyoffersnewinsightsintomechanismsofbreastcancerriskandresistance

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