Th17 cells favor inflammatory responses while inhibiting type I collagen deposition by dermal fibroblasts: differential effects in healthy and systemic sclerosis fibroblasts

INTRODUCTION: T helper (Th)-17 cells are increased in systemic sclerosis (SSc). We therefore assessed whether Th17 cells could modulate the inflammatory and fibrotic responses in dermal fibroblasts from healthy donors (HD) and SSc individuals. METHODS: Fibroblasts were obtained from 14 SSc and 8 HD...

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Detalles Bibliográficos
Autores principales: Brembilla, Nicolò Costantino, Montanari, Elisa, Truchetet, Marie-Elise, Raschi, Elena, Meroni, Pierluigi, Chizzolini, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979123/
https://www.ncbi.nlm.nih.gov/pubmed/24289089
http://dx.doi.org/10.1186/ar4334

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