Cargando…

Cytochrome P450 2E1 (CYP2E1) regulates the response to oxidative stress and migration of breast cancer cells

INTRODUCTION: The cytochrome P450 (CYP) enzymes are a class of heme-containing enzymes involved in phase I metabolism of a large number of xenobiotics. The CYP family member CYP2E1 metabolises many xenobiotics and pro-carcinogens, it is not just expressed in the liver but also in many other tissues...

Descripción completa

Detalles Bibliográficos
Autores principales:	Leung, Travis, Rajendran, Ramkumar, Singh, Subir, Garva, Richa, Krstic-Demonacos, Marija, Demonacos, Constantinos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979157/ https://www.ncbi.nlm.nih.gov/pubmed/24207099 http://dx.doi.org/10.1186/bcr3574

Ejemplares similares

Sirtuins: Molecular Traffic Lights in the Crossroad of Oxidative Stress, Chromatin Remodeling, and Transcription
por: Rajendran, Ramkumar, et al.
Publicado: (2011)

The role of glucocorticoid receptor phosphorylation in Mcl-1 and NOXA gene expression
por: Lynch, James T, et al.
Publicado: (2010)

Sirtuin Family Members Selectively Regulate Autophagy in Osteosarcoma and Mesothelioma Cells in Response to Cellular Stress
por: Garva, Richa, et al.
Publicado: (2019)

Roadmap to personalized medicine
por: Qattan, Malak, et al.
Publicado: (2012)

Protein disulfide isomerase A1-associated pathways in the development of stratified breast cancer therapies
por: Bakker, Emyr Yosef, et al.
Publicado: (2022)

The role of phosphorylated glucocorticoid receptor in mitochondrial functions and apoptotic signalling in brain tissue of stressed Wistar rats
por: Adzic, Miroslav, et al.
Publicado: (2009)

BAP1 Status Determines the Sensitivity of Malignant Mesothelioma Cells to Gemcitabine Treatment
por: Guazzelli, Alice, et al.
Publicado: (2019)

Dynamics of DNA Damage Induced Pathways to Cancer
por: Tian, Kun, et al.
Publicado: (2013)

Acute or chronic stress induce cell compartment-specific phosphorylation of glucocorticoid receptor and alter its transcriptional activity in Wistar rat brain
por: Adzic, Miroslav, et al.
Publicado: (2009)

Insight into glucocorticoid receptor signalling through interactome model analysis
por: Bakker, Emyr, et al.
Publicado: (2017)

Protein disulfide isomerase A1 regulates breast cancer cell immunorecognition in a manner dependent on redox state
por: Alhammad, Rashed, et al.
Publicado: (2020)

Differential regulation of cell death pathways by the microenvironment correlates with chemoresistance and survival in leukaemia
por: Qattan, Malak Yahia, et al.
Publicado: (2017)

Cytochrome P450 CYP2E1 Suppression Ameliorates Cerebral Ischemia Reperfusion Injury
por: Yu, Jin, et al.
Publicado: (2021)

Site-specific and dose-dependent effects of glucocorticoid receptor phosphorylation in yeast Saccharomyces cerevisiae
por: Popovic, Natasa, et al.
Publicado: (2010)

miR-663a regulates growth of colon cancer cells, after administration of antimicrobial peptides, by targeting CXCR4-p21 pathway
por: Kuroda, Kengo, et al.
Publicado: (2017)

Alteration in the Expression of Cytochrome P450s (CYP1A1, CYP2E1, and CYP3A11) in the Liver of Mouse Induced by Microcystin-LR
por: Zhang, Bangjun, et al.
Publicado: (2015)

Transgenic Zebrafish Expressing Rat Cytochrome P450 2E1 (CYP2E1): Augmentation of Acetaminophen-Induced Toxicity in the Liver and Retina
por: Sato, Yoshinori, et al.
Publicado: (2023)

Acetaldehyde and parkinsonism: role of CYP450 2E1
por: Vaglini, Francesca, et al.
Publicado: (2013)

p53 modeling as a route to mesothelioma patients stratification and novel therapeutic identification
por: Tian, Kun, et al.
Publicado: (2018)

Effects of Flavonoids in Lysimachia clethroides Duby on the Activities of Cytochrome P450 CYP2E1 and CYP3A4 in Rat Liver Microsomes
por: Zhang, Zhi-Juan, et al.
Publicado: (2016)

The cytochrome P450 (CYP) superfamily in cnidarians
por: Pankov, Kirill V., et al.
Publicado: (2021)

Structural basis of steroid binding and oxidation by the cytochrome P450 CYP109E1 from Bacillus megaterium
por: Jóźwik, Ilona K., et al.
Publicado: (2016)

Modeling the Mechanism of GR/c-Jun/Erg Crosstalk in Apoptosis of Acute Lymphoblastic Leukemia
por: Chen, Daphne Wei-Chen, et al.
Publicado: (2012)

Melatonin Activation by Cytochrome P450 Isozymes: How Does CYP1A2 Compare to CYP1A1?
por: Mokkawes, Thirakorn, et al.
Publicado: (2023)

Genetic polymorphisms of cytochrome P450-1A2 (CYP1A2) among Emiratis
por: Al-Ahmad, Mohammad M., et al.
Publicado: (2017)

The Frequency of Cytochrome P450 2E1 Polymorphisms in Black South Africans
por: Chelule, Paul K., et al.
Publicado: (2006)

The role of human cytochrome P450 2E1 in liver inflammation and fibrosis
por: Xu, Jun, et al.
Publicado: (2017)

Role of Mitochondrial Cytochrome P450 2E1 in Healthy and Diseased Liver
por: Massart, Julie, et al.
Publicado: (2022)

In vitro and In silico studies of interactions of cathinone with human recombinant cytochrome P450 CYP(1A2), CYP2A6, CYP2B6, CYP2C8, CYP2C19, CYP2E1, CYP2J2, and CYP3A5
por: Lim, Sharoen Yu Ming, et al.
Publicado: (2022)

Identification of cytochrome P450 gene family and functional analysis of HgCYP33E1 from Heterodera glycines
por: You, Jia, et al.
Publicado: (2023)

Validation of an HPLC Method for the Simultaneous Quantification of Metabolic Reaction Products Catalysed by CYP2E1 Enzyme Activity: Inhibitory Effect of Cytochrome P450 Enzyme CYP2E1 by Salicylic Acid in Rat Liver Microsomes
por: Salhab, Hassan, et al.
Publicado: (2020)

Succinic acid inhibits the activity of cytochrome P450 (CYP450) enzymes
por: Wang, Hao, et al.
Publicado: (2020)

Cytochrome P450 CYP1B1 activity in renal cell carcinoma
por: McFadyen, M C E, et al.
Publicado: (2004)

A Comparative Genomic and Phylogenetic Investigation of the Xenobiotic Metabolism Enzymes of Cytochrome P450 in Elephants Shows Loss in CYP2E and CYP4A
por: Watanabe, Kanami, et al.
Publicado: (2023)

Cytochrome P450-2E1 promotes fast food-mediated hepatic fibrosis
por: Abdelmegeed, Mohamed A., et al.
Publicado: (2017)

Analysis of polymorphisms of canine Cytochrome P 450‐CYP2D15
por: van Hagen, Marjan A. E., et al.
Publicado: (2020)

Bioactivation of Aromatic Amines by Human CYP2W1, An Orphan Cytochrome P450 Enzyme
por: Eun, Chang-Yong, et al.
Publicado: (2010)

Intratumor microbiota as a novel potential prognostic indicator in mesothelioma
por: Pentimalli, Francesca, et al.
Publicado: (2023)

Cytochrome P2E1 (CYP2E1) Gene Polymorphism as a Potential Prognostic Biomarker in Colorectal Cancer
por: Moghadas, Ayda, et al.
Publicado: (2023)

Identification of 74 cytochrome P450 genes and co-localized cytochrome P450 genes of the CYP2K, CYP5A, and CYP46A subfamilies in the mangrove killifish Kryptolebias marmoratus
por: Lee, Bo-Young, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_nsf4iim51akm4333an9s301r5m