MIDAZOLAM PREMEDICATION IN ATTENUATING KETAMINE PSYCHIC SEQUELAE

The objective of the study was to evaluate the effectiveness of midazolam premedication in attenuating the psychic sequelae of ketamine dissociative anaesthesia. Sixty patients undergoing various short surgical and urological procedures were taken in the study. All patients were premedicated with mi...

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Autores principales: Somashekara, S. C., Govindadas, D., Devashankaraiah, G., Mahato, Rajkishore, Deepalaxmi, S., Srinivas, V., Murugesh, J. V., Devanand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979212/
https://www.ncbi.nlm.nih.gov/pubmed/24825990
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author Somashekara, S. C.
Govindadas, D.
Devashankaraiah, G.
Mahato, Rajkishore
Deepalaxmi, S.
Srinivas, V.
Murugesh, J. V.
Devanand,
author_facet Somashekara, S. C.
Govindadas, D.
Devashankaraiah, G.
Mahato, Rajkishore
Deepalaxmi, S.
Srinivas, V.
Murugesh, J. V.
Devanand,
author_sort Somashekara, S. C.
collection PubMed
description The objective of the study was to evaluate the effectiveness of midazolam premedication in attenuating the psychic sequelae of ketamine dissociative anaesthesia. Sixty patients undergoing various short surgical and urological procedures were taken in the study. All patients were premedicated with midazolam (0.05mg/kg i.v) five minutes before ketamine induction (1mg/kg i.v). The excitatory phenomenon, emergence delirium, occurrence of unpleasant dreams and patient acceptability of ketamine anaesthesia were recorded. Out of 60 patients studied, 15% had excitatory effects, 8% had mild delirium and 3% patients had unpleasant dreams in post operative period. Patient acceptability of ketamine anaesthesia was 100%. Hence from the study it was concluded that, midazolam premedication is effective in attenuating ketamine psychic sequelae
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spelling pubmed-39792122014-05-13 MIDAZOLAM PREMEDICATION IN ATTENUATING KETAMINE PSYCHIC SEQUELAE Somashekara, S. C. Govindadas, D. Devashankaraiah, G. Mahato, Rajkishore Deepalaxmi, S. Srinivas, V. Murugesh, J. V. Devanand, J Basic Clin Pharm Original Article The objective of the study was to evaluate the effectiveness of midazolam premedication in attenuating the psychic sequelae of ketamine dissociative anaesthesia. Sixty patients undergoing various short surgical and urological procedures were taken in the study. All patients were premedicated with midazolam (0.05mg/kg i.v) five minutes before ketamine induction (1mg/kg i.v). The excitatory phenomenon, emergence delirium, occurrence of unpleasant dreams and patient acceptability of ketamine anaesthesia were recorded. Out of 60 patients studied, 15% had excitatory effects, 8% had mild delirium and 3% patients had unpleasant dreams in post operative period. Patient acceptability of ketamine anaesthesia was 100%. Hence from the study it was concluded that, midazolam premedication is effective in attenuating ketamine psychic sequelae Medknow Publications & Media Pvt Ltd 2010-09 2010-11-15 /pmc/articles/PMC3979212/ /pubmed/24825990 Text en Copyright: © Journal of Basic and Clinical Pharmacy http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Somashekara, S. C.
Govindadas, D.
Devashankaraiah, G.
Mahato, Rajkishore
Deepalaxmi, S.
Srinivas, V.
Murugesh, J. V.
Devanand,
MIDAZOLAM PREMEDICATION IN ATTENUATING KETAMINE PSYCHIC SEQUELAE
title MIDAZOLAM PREMEDICATION IN ATTENUATING KETAMINE PSYCHIC SEQUELAE
title_full MIDAZOLAM PREMEDICATION IN ATTENUATING KETAMINE PSYCHIC SEQUELAE
title_fullStr MIDAZOLAM PREMEDICATION IN ATTENUATING KETAMINE PSYCHIC SEQUELAE
title_full_unstemmed MIDAZOLAM PREMEDICATION IN ATTENUATING KETAMINE PSYCHIC SEQUELAE
title_short MIDAZOLAM PREMEDICATION IN ATTENUATING KETAMINE PSYCHIC SEQUELAE
title_sort midazolam premedication in attenuating ketamine psychic sequelae
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979212/
https://www.ncbi.nlm.nih.gov/pubmed/24825990
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