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In vitro antioxidant activity and HPTLC determination of n-hexane extract of Emilia sonchifolia (L.)DC.

The free radical scavenging activities of n-hexane extract of the whole plant of Emilia sonchifolia was evaluated by employing various in vitro assay systems like DPPH radical scavenging activity, superoxide radical scavenging activity and hydrogen peroxide scavenging activity with IC(50) values 180...

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Autores principales: Sophia, D., Ragavendran, P., Arulraj, C., Gopalakrishnan, V. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979225/
https://www.ncbi.nlm.nih.gov/pubmed/24826021
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author Sophia, D.
Ragavendran, P.
Arulraj, C.
Gopalakrishnan, V. K.
author_facet Sophia, D.
Ragavendran, P.
Arulraj, C.
Gopalakrishnan, V. K.
author_sort Sophia, D.
collection PubMed
description The free radical scavenging activities of n-hexane extract of the whole plant of Emilia sonchifolia was evaluated by employing various in vitro assay systems like DPPH radical scavenging activity, superoxide radical scavenging activity and hydrogen peroxide scavenging activity with IC(50) values 180, 160 and 160 μg/ml respectively. The results of the study indicate that the n-hexane extract of the whole plant of Emilia sonchifolia possess a significant scavenging effect with increasing concentrations probably due to its antioxidant potential. High performance thin layer chromatography (HPTLC) analysis in the n-hexane extract of Emilia sonchifolia showed the presence of terpenoids which probably may be responsible for the antioxidant activity. Thus, n-hexane extract of Emilia sonchifolia can be used potentially as a bioactive source of natural antioxidants due to the presence of terpenoids in it
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spelling pubmed-39792252014-05-13 In vitro antioxidant activity and HPTLC determination of n-hexane extract of Emilia sonchifolia (L.)DC. Sophia, D. Ragavendran, P. Arulraj, C. Gopalakrishnan, V. K. J Basic Clin Pharm Original Article The free radical scavenging activities of n-hexane extract of the whole plant of Emilia sonchifolia was evaluated by employing various in vitro assay systems like DPPH radical scavenging activity, superoxide radical scavenging activity and hydrogen peroxide scavenging activity with IC(50) values 180, 160 and 160 μg/ml respectively. The results of the study indicate that the n-hexane extract of the whole plant of Emilia sonchifolia possess a significant scavenging effect with increasing concentrations probably due to its antioxidant potential. High performance thin layer chromatography (HPTLC) analysis in the n-hexane extract of Emilia sonchifolia showed the presence of terpenoids which probably may be responsible for the antioxidant activity. Thus, n-hexane extract of Emilia sonchifolia can be used potentially as a bioactive source of natural antioxidants due to the presence of terpenoids in it Medknow Publications & Media Pvt Ltd 2011-09 2011-11-15 /pmc/articles/PMC3979225/ /pubmed/24826021 Text en Copyright: © Journal of Basic and Clinical Pharmacy http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Sophia, D.
Ragavendran, P.
Arulraj, C.
Gopalakrishnan, V. K.
In vitro antioxidant activity and HPTLC determination of n-hexane extract of Emilia sonchifolia (L.)DC.
title In vitro antioxidant activity and HPTLC determination of n-hexane extract of Emilia sonchifolia (L.)DC.
title_full In vitro antioxidant activity and HPTLC determination of n-hexane extract of Emilia sonchifolia (L.)DC.
title_fullStr In vitro antioxidant activity and HPTLC determination of n-hexane extract of Emilia sonchifolia (L.)DC.
title_full_unstemmed In vitro antioxidant activity and HPTLC determination of n-hexane extract of Emilia sonchifolia (L.)DC.
title_short In vitro antioxidant activity and HPTLC determination of n-hexane extract of Emilia sonchifolia (L.)DC.
title_sort in vitro antioxidant activity and hptlc determination of n-hexane extract of emilia sonchifolia (l.)dc.
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979225/
https://www.ncbi.nlm.nih.gov/pubmed/24826021
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