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In vitro antioxidant activity and HPTLC determination of n-hexane extract of Emilia sonchifolia (L.)DC.
The free radical scavenging activities of n-hexane extract of the whole plant of Emilia sonchifolia was evaluated by employing various in vitro assay systems like DPPH radical scavenging activity, superoxide radical scavenging activity and hydrogen peroxide scavenging activity with IC(50) values 180...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979225/ https://www.ncbi.nlm.nih.gov/pubmed/24826021 |
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author | Sophia, D. Ragavendran, P. Arulraj, C. Gopalakrishnan, V. K. |
author_facet | Sophia, D. Ragavendran, P. Arulraj, C. Gopalakrishnan, V. K. |
author_sort | Sophia, D. |
collection | PubMed |
description | The free radical scavenging activities of n-hexane extract of the whole plant of Emilia sonchifolia was evaluated by employing various in vitro assay systems like DPPH radical scavenging activity, superoxide radical scavenging activity and hydrogen peroxide scavenging activity with IC(50) values 180, 160 and 160 μg/ml respectively. The results of the study indicate that the n-hexane extract of the whole plant of Emilia sonchifolia possess a significant scavenging effect with increasing concentrations probably due to its antioxidant potential. High performance thin layer chromatography (HPTLC) analysis in the n-hexane extract of Emilia sonchifolia showed the presence of terpenoids which probably may be responsible for the antioxidant activity. Thus, n-hexane extract of Emilia sonchifolia can be used potentially as a bioactive source of natural antioxidants due to the presence of terpenoids in it |
format | Online Article Text |
id | pubmed-3979225 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-39792252014-05-13 In vitro antioxidant activity and HPTLC determination of n-hexane extract of Emilia sonchifolia (L.)DC. Sophia, D. Ragavendran, P. Arulraj, C. Gopalakrishnan, V. K. J Basic Clin Pharm Original Article The free radical scavenging activities of n-hexane extract of the whole plant of Emilia sonchifolia was evaluated by employing various in vitro assay systems like DPPH radical scavenging activity, superoxide radical scavenging activity and hydrogen peroxide scavenging activity with IC(50) values 180, 160 and 160 μg/ml respectively. The results of the study indicate that the n-hexane extract of the whole plant of Emilia sonchifolia possess a significant scavenging effect with increasing concentrations probably due to its antioxidant potential. High performance thin layer chromatography (HPTLC) analysis in the n-hexane extract of Emilia sonchifolia showed the presence of terpenoids which probably may be responsible for the antioxidant activity. Thus, n-hexane extract of Emilia sonchifolia can be used potentially as a bioactive source of natural antioxidants due to the presence of terpenoids in it Medknow Publications & Media Pvt Ltd 2011-09 2011-11-15 /pmc/articles/PMC3979225/ /pubmed/24826021 Text en Copyright: © Journal of Basic and Clinical Pharmacy http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Sophia, D. Ragavendran, P. Arulraj, C. Gopalakrishnan, V. K. In vitro antioxidant activity and HPTLC determination of n-hexane extract of Emilia sonchifolia (L.)DC. |
title | In vitro antioxidant activity and HPTLC determination of n-hexane extract of Emilia sonchifolia (L.)DC. |
title_full | In vitro antioxidant activity and HPTLC determination of n-hexane extract of Emilia sonchifolia (L.)DC. |
title_fullStr | In vitro antioxidant activity and HPTLC determination of n-hexane extract of Emilia sonchifolia (L.)DC. |
title_full_unstemmed | In vitro antioxidant activity and HPTLC determination of n-hexane extract of Emilia sonchifolia (L.)DC. |
title_short | In vitro antioxidant activity and HPTLC determination of n-hexane extract of Emilia sonchifolia (L.)DC. |
title_sort | in vitro antioxidant activity and hptlc determination of n-hexane extract of emilia sonchifolia (l.)dc. |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979225/ https://www.ncbi.nlm.nih.gov/pubmed/24826021 |
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