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IN VITRO ASSESSMENT OF THE BIOLOGIC ACTIVITY OF INTERFERON BETA FORMULATIONS USED FOR THE TREATMENT OF RELAPSING MULTIPLE SCLEROSIS

□ A new formulation (NF) of subcutaneous (sc) interferon (IFN) β-1a was developed in an attempt to improve injection tolerability and immunogenicity. We compared antiviral and IFNβ-stimulated gene (ISG) activities of IFNβ-1a sc NF with IFNβ-1a sc original formulation and IFNβ-1b sc. When equivalent...

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Detalles Bibliográficos
Autores principales: Scagnolari, Carolina, Selvaggi, Carla, Di Biase, Emilia, Fraulo, Maurizio, Dangond, Fernando, Antonelli, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979447/
https://www.ncbi.nlm.nih.gov/pubmed/24654824
http://dx.doi.org/10.1080/15321819.2013.848815