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Ligand Photo-Isomerization Triggers Conformational Changes in iGluR2 Ligand Binding Domain
Neurological glutamate receptors bind a variety of artificial ligands, both agonistic and antagonistic, in addition to glutamate. Studying their small molecule binding properties increases our understanding of the central nervous system and a variety of associated pathologies. The large, oligomeric...
Autores principales: | Wolter, Tino, Steinbrecher, Thomas, Trauner, Dirk, Elstner, Marcus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979659/ https://www.ncbi.nlm.nih.gov/pubmed/24713651 http://dx.doi.org/10.1371/journal.pone.0092716 |
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