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Vasoreparative Dysfunction of CD34(+) Cells in Diabetic Individuals Involves Hypoxic Desensitization and Impaired Autocrine/Paracrine Mechanisms
We hypothesized that endothelial progenitor cells derived from individuals with diabetes would exhibit functional defects including inability to respond to hypoxia and altered paracrine/autocrine function that would impair the angiogenic potential of these cells. Circulating mononuclear cells isolat...
Autores principales: | Jarajapu, Yagna P. R., Hazra, Sugata, Segal, Mark, LiCalzi, Sergio, Jhadao, Chandra, Qian, Kevin, Mitter, Sayak K., Raizada, Mohan K., Boulton, Michael E., Grant, Maria B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979711/ https://www.ncbi.nlm.nih.gov/pubmed/24713821 http://dx.doi.org/10.1371/journal.pone.0093965 |
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